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How to Change a Memory

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A disarmingly personal account of the new science of memory manipulation by one of today’s leading pioneers in the fieldAs a graduate student at MIT, Steve Ramirez successfully created false memori...
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  • 04 November 2025
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A disarmingly personal account of the new science of memory manipulation by one of today’s leading pioneers in the field

As a graduate student at MIT, Steve Ramirez successfully created false memories in the lab. Now, as a neuroscientist working at the frontiers of brain science, he foresees a future where we can replace our negative memories with positive ones. In How to Change a Memory, Ramirez draws on his own memories—of friendship, family, loss, and recovery—to reveal how memory can be turned on and off like a switch, edited, and even constructed from nothing.

A future in which we can change our memories of the past may seem improbable, but in fact, the everyday act of remembering is one of transformation. Intentionally editing memory to improve our lives takes advantage of the brain’s natural capacity for change.

In How to Change a Memory, Ramirez explores how scientists discovered that memories are fluid—they change over time, can be erased, reactivated, and even falsely implanted in the lab. Reflecting on his own path as a scientist, he examines how memory manipulation shapes our imagination and sense of self. If we can erase a deeply traumatic memory, would it change who we are? And what would that change mean anyway? Throughout, Ramirez carefully considers the ethics of artificially controlling memory, exploring how we might use this tool responsibly—for both personal healing and the greater good.

A masterful blend of memoir and cutting-edge science, How to Change a Memory explores how neuroscience has reached a critical juncture, where scientists can see the potential of memory manipulation to help people suffering from the debilitating effects of PTSD, anxiety, Alzheimer’s, addiction, and a host of other neurological and behavioral disorders.

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Price: $29.95
Pages: 256
Publisher: Princeton University Press
Imprint: Princeton University Press
Publication Date: 04 November 2025
ISBN: 9780691266688
Format: Hardcover
BISACs:

SCIENCE / Life Sciences / Neuroscience, Physiological and neuro-psychology, biopsychology, PSYCHOLOGY / Neuropsychology, SCIENCE / Cognitive Science, Neurosciences

"[Ramirez’s] storytelling moves fluidly between memoir and science writing, blending lab anecdotes with personal reflections in a way that makes even the most technical discoveries feel intimate. . . . For students and young scientists, the book is a beacon—it shows that science does not demand that we hide our imperfections and that our fragilities and limits can coexist with creativity and rigor, reminding readers that discovery is a deeply human pursuit rather than a purely technical one. For nonexpert readers, it delivers complex neuroscience in a form that is intimate, relatable, and often funny."---Gisella Vetere, Science
Steve Ramirez has been featured on CNN, NPR, and the BBC and in leading publications such as The New York Times, National Geographic, Wired, Forbes, The Guardian, The Economist, and Nature. An award-winning neuroscientist who has given TED talks on his groundbreaking work on memory manipulation, he is associate professor of psychological and brain sciences at Boston University.