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What Would You Do Alone in a Cage with Nothing but Cocaine?

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A revolutionary new paradigm for understanding addictionWhy do people with addiction use drugs self-destructively? Why don’t they quit out of self-concern? Why does the rat in the experiment, alone...
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  • 06 January 2026
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A revolutionary new paradigm for understanding addiction

Why do people with addiction use drugs self-destructively? Why don’t they quit out of self-concern? Why does the rat in the experiment, alone in a cage, press the lever again and again for cocaine—to the point of death? In this pathbreaking book, Hanna Pickard proposes a new paradigm for understanding the puzzle of addiction. For too long, our thinking has been hostage to a false dichotomy: either addiction is a brain disease, or it is a moral failing. Pickard argues that it is neither, and that both models stifle addiction research and fail people who need help.

Drawing on her expertise as an academic philosopher and her clinical work in a therapeutic community, Pickard explores the meaning of drugs for people with addiction and the diverse factors that keep them using despite the costs. People use drugs to cope with suffering—but also to self-harm, or even to die. Some identify as “addicts," while others are in denial or struggle with cravings and self-control. Social, cultural, and economic circumstances are crucial to explaining addiction—but brain pathology may also matter. By integrating addiction science with philosophy, clinical practice, and the psychology and voices of people with addiction themselves, Pickard shows why there is no one-size-fits-all theory or ethics of addiction. The result is a heterogeneous and humanistic paradigm for understanding and treating addiction, and a fresh way of thinking about responsibility, blame, and relationships with people who use drugs.

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Price: $29.95
Pages: 352
Publisher: Princeton University Press
Imprint: Princeton University Press
Publication Date: 06 January 2026
ISBN: 9780691253534
Format: Hardcover
BISACs:

PSYCHOLOGY / Psychopathology / Addiction, Addiction and therapy, PSYCHOLOGY / Cognitive Neuroscience & Cognitive Neuropsychology, PHILOSOPHY / Mind & Body, Physiological and neuro-psychology, biopsychology, Cognition and cognitive psychology, Health psychology, Cognitive and behavioural neuroscience

"A brilliant and compelling contribution...that has the potential to reframe the public’s understanding of drug use and addiction. . . . It is a text rooted in radical compassion that supports autonomy, promotes responsibility without blame, and highlights the various factors that can cause and maintain an individual’s substance use over time."---Cassandra L. Boness, Science
Hanna Pickard is Bloomberg Distinguished Professor of Philosophy and Bioethics and Krieger-Eisenhower Professor at Johns Hopkins University.